5 years ago

Preparation, characterization, and in vitro evaluation of chicken feather fiber–thermoplastic polyurethane composites

Preparation, characterization, and in vitro evaluation of chicken feather fiber–thermoplastic polyurethane composites
Gurler Akpinar, Guralp Ozkoc, Murat Kasap, Ozge Gokce
In this study, we aimed to investigate the potential use of keratin biofiber (KBF)-reinforced biodegradable thermoplastic polyurethane (TPU) composites as tissue engineering scaffolds. The composites were prepared by a solution casting method. Combined salt leaching and thermally induced phase-separation methods were used to manufacture porous scaffold structures. The mechanical properties were investigated with tensile tests and dynamic mechanical analysis (DMA). An increase in the fiber content increased the modulus and strength of the composites. The DMA results revealed that the storage modulus of the composites compared to that of the neat TPU was improved by the addition of feathers. Scanning electron microscopy analysis indicated that the dispersion of KBF in the TPU matrix was uniform. According to the water contact angle measurements, the hydrophilicity increased with increasing KBF content up to 80%. The thermal properties of the KBF–TPU films were measured by a differential scanning calorimetry method. The increase in the amount of KBF did not significantly affect the glass-transition temperature values. We examined the cytotoxicity and biocompatibility by performing cell culturing with the L929 mouse fibroblast cell line. The cell viability was found to be greater than 80% for all of the scaffold compositions. This showed that the KBF–TPU composite scaffolds may serve as a highly potent new material for skin tissue engineering applications. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45338.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/app.45338

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.