3 years ago

Coordination-Driven Self-Assembly of Ionic Irregular Hexagonal Metallamacrocycles via an Organometallic Clip and Their Cytotoxicity Potency

Coordination-Driven Self-Assembly of Ionic Irregular Hexagonal Metallamacrocycles via an Organometallic Clip and Their Cytotoxicity Potency
Sourav Bhowmick, Prerak Gupta, Khushwant Singh, Biman B. Mandal, Ankit Gangrade, Neeladri Das, Achintya Jana
Two new molecular hexagons were synthesized using a new organometallic acceptor clip [bearing two platinum(II) centers] and neutral donor ligands via a coordination-driven self-assembly protocol. Macrocycles are unique examples of [2 + 2] ensembles that are hexagonal in shape. Their construction requires the assembly of only four subunits. The cytotoxicity of platinum(II)-based macrocycles was studied using various cancer cell lines, and the results were compared with those of cisplatin.

Publisher URL: http://dx.doi.org/10.1021/acs.inorgchem.7b01561

DOI: 10.1021/acs.inorgchem.7b01561

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