Biotechnology and Bioengineering
Biotechnology and Bioengineering
4 years ago

An adjustable multi-scale single beam acoustic tweezers based on ultrahigh frequency ultrasonic transducer

An adjustable multi-scale single beam acoustic tweezers based on ultrahigh frequency ultrasonic transducer
K. Kirk Shung, Ruimin Chen, Qifa Zhou, Zhongping Chen, Ping Yu, Xiaoyang Chen, Zeyu Chen, Kwok Ho Lam
This paper reports the fabrication, characterization, and microparticle manipulation capability of an adjustable multi-scale single beam acoustic tweezers (SBAT) that is capable of flexibly changing the size of “tweezers” like ordinary metal tweezers with a single-element ultrahigh frequency (UHF) ultrasonic transducer. The measured resonant frequency of the developed transducer at 526 MHz is the highest frequency of piezoelectric single crystal based ultrasonic transducers ever reported. This focused UHF ultrasonic transducer exhibits a wide bandwidth (95.5% at −10 dB) due to high attenuation of high-frequency ultrasound wave, which allows the SBAT effectively excite with a wide range of excitation frequency from 150 to 400 MHz by using the “piezoelectric actuator” model. Through controlling the excitation frequency, the wavelength of ultrasound emitted from the SBAT can be changed to selectively manipulate a single microparticle of different sizes (3–100 μm) by using only one transducer. This concept of flexibly changing “tweezers” size is firstly introduced into the study of SBAT. At the same time, it was found that this incident ultrasound wavelength play an important role in lateral trapping and manipulation for microparticle of different sizes. Biotechnol. Bioeng. 2017;9999: 1–11. © 2017 Wiley Periodicals, Inc. An excellent microparticle-handling tweezers should be capable of selectively manipulating objects with a large range of size from the concept of tweezers, like ordinary metal tweezers. This is very helpful for the targeted microparticle manipulation. Here, Xiaoyang and coworkers develop a more advanced single beam acoustic tweezers (SBAT) which have the capability of selectively manipulating microparticles with wide size range of 3–100 µm using only one transducer by flexibly adjusting beam width or ultrasound wavelength.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/bit.26365

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