4 years ago

Cell Polarity: Spot-On Cdc42 Polarization Achieved on Demand

Cell Polarity: Spot-On Cdc42 Polarization Achieved on Demand
Marcin Leda, Andrew B. Goryachev


A new study deploys optogenetics to induce the yeast bud on demand, at a site determined by a laser spot. The authors definitively prove that the initiation of cell polarization is driven by the Bem1-mediated positive feedback loop and reveal novel features of its regulation by the cell cycle.

Publisher URL: http://www.cell.com/current-biology/fulltext/S0960-9822(17)30864-3

DOI: 10.1016/j.cub.2017.07.006

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