5 years ago

Ribosomal Architecture: Constraints Imposed by the Need for Self-Production

Ribosomal Architecture: Constraints Imposed by the Need for Self-Production
Hendrik Osadnik, Jeffrey A. Hussmann, Carol A. Gross


Ribosomes contain proteins that must themselves be made by ribosomes. A new study shows that splitting ribosomal protein content into many small, similarly sized units maximizes the efficiency of this synthesis, suggesting that ribosomal architecture has been shaped by evolutionary pressure to efficiently self-synthesize.

Publisher URL: http://www.cell.com/current-biology/fulltext/S0960-9822(17)30853-9

DOI: 10.1016/j.cub.2017.06.080

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