Journal of Minimally Invasive Gynecology
Journal of Minimally Invasive Gynecology
5 years ago

Irrigation after Laparoscopic Power Morcellation and the Dispersal of Leiomyoma Cells: a Pilot Study

To evaluate if copious irrigation and suctioning after electro-mechanical power morcellation will reduce myoma cell dissemination, and if there is a difference between sterile water and normal saline. Design Prospective single-center cohort pilot study (Canadian Task Force Classification II-2) Setting Academic tertiary referral center Patients Sixteen women undergoing laparoscopic myomectomy with one surgeon between January 1, 2017 and August 31, 2017. Interventions Peritoneal washings were collected three specific times during surgery: after dissection of myoma(s) and hysterotomy repair but before morcellation, after morcellation, and after irrigation with 3 L of normal saline or sterile water. The primary outcome was the detection of benign spindle cells (BSC) in peritoneal washings. Measurements and Main Results Sixteen subjects were enrolled in the study. Eight were randomized to the normal saline group and eight were randomized to the sterile water group. In the normal saline group, BSC were detected in 3 of 8 (37.5%) subjects following closure of the hysterotomy, but before morcellation, in 3 of 8 (37.5%) after morcellation, and in 0 of 8 (0%) after irrigation and suctioning of the peritoneal cavity with 3 L of normal saline. In the sterile water group, BSC were detected in 3 of 8 (37.5%) subjects following closure of the hysterotomy, but before morcellation, 2 of 8 (25%) after morcellation, and in 0 of 8 (0%) after irrigation and suctioning with 3 L of sterile water. Thus no differences were found between the normal saline and sterile water groups. Conclusion In this pilot study, myoma cells were disseminated before electro-mechanical morcellation. Irrigation and suctioning with 3 L of normal saline or sterile water after morcellation may reduce myoma cell dissemination.

Publisher URL: www.sciencedirect.com/science

DOI: S1553465018300785

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