Organic Letters
Organic Letters
5 years ago

Manganese(I)-Catalyzed C–H 3,3-Difluoroallylation of Pyridones and Indoles

Manganese(I)-Catalyzed C–H 3,3-Difluoroallylation of Pyridones and Indoles
Ao Zhang, Jiabin Ni, Hongchuan Zhao
A novel and efficient C–H activation approach for the direct 3,3-difluoroallylation of 2-pyridones and indoles is herein reported using a manganese(I) complex as the catalyst. A broad range of substrates with diverse functional groups were tolerated. Moreover, late-stage C–H functionalization of bioactive molecules was achieved in good yield.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b01282

DOI: 10.1021/acs.orglett.7b01282

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.