AMPK Wars: the VMH Strikes Back, Return of the PVH
Hypothalamic AMP-activated protein kinase (AMPK) is an important modulator of whole-body energy homeostasis, particularly within the ventromedial nucleus, where it regulates energy expenditure, glucose, and lipid metabolism. A recent paper in Cell Reports has demonstrated that AMPK in the paraventricular nucleus of the hypothalamus modulates dietary preference for carbohydrate over fat.
Publisher URL: http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(18)30005-5
DOI: 10.1016/j.tem.2018.01.004
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