Chemistry - A European Journal
Chemistry - A European Journal
5 years ago

Frontispiece: Metalated Chromene and Chromone Complexes: pH Switchable Metal–Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity

Frontispiece: Metalated Chromene and Chromone Complexes: pH Switchable Metal–Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity
Chi-Fung Yeung, Lai-Hon Chung, Hoi-Shing Lo, Chung-Hang Leung, Tian-Shu Kang, Dik-Lung Ma, Sze-Wing Ng, Hau-Lam Shek, Chun-Yuen Wong
Despite numerous studies on organic chromones, investigation on metalated chromene and chromone complexes lags far behind. In this work, metalated chromene and chromone complexes with superior antioxidative property were prepared by ruthenium-mediated cyclization of phenol-tethered ynone. The liberation of free chromone from the complexes was triggered by blue-light irradiation. This work highlights the potential application of metalated chromene and chromone complexes on controlled drug release. More information can be found in the Communication by C.-Y. Wong et al. on page 1779 ff.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201880864

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