Medical Physics
Medical Physics
5 years ago

Material Elemental Decomposition in Dual and Multi-energy CT via a Sparsity-Dictionary Approach for Proton Stopping Power Ratio Calculation.

Xun Jia, Chenyang Shen, Yifei Lou, Bin Li, Ming Yang, Liyuan Chen
Accurate calculation of proton stopping power ratio (SPR) relative to water is crucial to proton therapy treatment planning, since SPR affects prediction of beam range. Current standard practice derives SPR using a single CT scan. Recent studies showed that dual-energy CT (DECT) offers advantages to accurately determine SPR. One method to further improve accuracy is to incorporate prior knowledge on human tissue composition through a dictionary approach. In addition, it is also suggested that using CT images with multiple (more than two) energy channels, i.e. multi-energy CT (MECT), can further improve accuracy. In this paper, we proposed a sparse dictionary-based method to convert CT numbers of DECT or MECT to elemental composition (EC) and relative electron density (rED) for SPR computation.

Publisher URL: http://doi.org/10.1002/mp.12796

DOI: 10.1002/mp.12796

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