Organic Letters
Organic Letters
5 years ago

Construction of Benzene Rings by Copper-Catalyzed Cycloaddition Reactions of Oximes and Maleimides: An Access to Fused Phthalimides

Construction of Benzene Rings by Copper-Catalyzed Cycloaddition Reactions of Oximes and Maleimides: An Access to Fused Phthalimides
Si Sun, Ying Ye, Yue Xi, Bo Zhao, Ye Wei, Zhen Yang, Jie Yang, Kun Jiang
A useful Cu-catalyzed cycloaddition protocol for the construction of benzene rings has been achieved. The reactions, utilizing readily available oximes and maleimides as starting materials, proceed under mild reaction conditions to generate a series of structurally interesting fused-phthalimides that are difficult to be prepared by conventional methods.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.8b00141

DOI: 10.1021/acs.orglett.8b00141

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