4 years ago

Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling

Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling
Debasis Dey, Babu Sudhamalla, Tiffany Nguyen, Megan Breski, Kabirul Islam
The hydrophobic pocket of the epigenetic reader protein BRD4 has been engineered to carry a photosensitive amino acid to identify novel interacting partners, providing mechanistic insights into BRD4's function in transcription and beyond.

Publisher URL: http://feeds.rsc.org/~r/rss/SC/~3/A7nZdfVu8fI/C7SC00284J

DOI: 2017/SC/C7SC00284J

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