American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine
5 years ago

Regulatory T Cells Subvert Mycobacterial Containment in Patients Failing Extensively Drug-resistant TB Treatment.

Anke Binder, Elize Pietersen, Malika Davids, Keertan Dheda, Anil S Pooran, Helen C Wainwright, Robin Warren
The advent of extensively (XDR-TB) and totally drug-resistant TB, with limited or no treatment options, has facilitated renewed interest in host directed immunotherapy, particularly for therapeutically destitute patients. However, the selection and utility of such approaches depend upon understanding the host immune response in XDR-TB, which hitherto remains unexplored.

Publisher URL: http://doi.org/10.1164/rccm.201707-1441OC

DOI: 10.1164/rccm.201707-1441OC

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