Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis.

5 years ago

Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis.

Luting Xu, Victoria Chapman, Robert H Morris, Oksana Kehoe, Paul Mapp, Alicia J El Haj, Alasdair Kay, Hareklea Markides, James J Burston, Devi Rani Sagar

Mesenchymal stem cells (MSCs) have a therapeutic potential for the treatment of osteoarthritic (OA) joint pathology and pain. The aims of this study were to determine the influence of a passage number on the effects of MSCs on pain behaviour and cartilage and bone features in a rodent model of OA.

Publisher URL: http://doi.org/10.1155/2017/2905104

DOI: 10.1155/2017/2905104

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