British Journal of Dermatology
British Journal of Dermatology
5 years ago

开发和验证皮肤疣(CWARTS)诊断工具:一种新型皮肤疣临床评估和分类系统

K.E. Hermans, M.N.C. de Koning, G.K. Hogendoorn, S.C. Bruggink, J.A.H. Eekhof, K.D. Quint, J.N. Bouwes Bavinck, R. Rissmann, S.T.P. Kouwenhoven, R. Wolterbeek, J. Burggraaf
并非所有皮肤疣的症状都相同。这项在荷兰开展的研究旨在开发并测试精确的诊断工具,以帮助临床医生诊断疣。该项研究的作者根据各种文献和专家访谈定义了九大外观特征,进而开发出了皮肤疣诊断工具(CWARTS诊断工具)。该项研究包括两个部分。在第一个部分(部分A)中,28名研究人员(“观察员”)评估了10种疣的照片,然后该团队调查了这些研究人员之间的共识程度。在第二个部分(部分B)中,6名研究人员再次评估了299种疣的照片,这次该团队测试了这6名观察员的第一次和第二次(相隔一周或更久)评估结果的一致性。对于疣的九种特征,该团队计算了一种广泛使用的可靠性指数,称为同类相关系数(ICC)。换句话说,如果ICC较高,则说明观察员之间达成共识的程度较高或者观察员的结果更加一致。观察员对存在黑点的这一特征的共识程度最高(达到0.85),疣的排列次之(0.65),接着是疣的边缘有红斑(0.64)以及边缘的对比(0.60)。在研究的部分B中,这些结果较为相似。对于第一次和第二次评估之间的一致性,存在黑点这一特征再一次位列第一,其次是边缘有红斑(0.64)以及疣的颜色(0.55)。作者们通过此项研究论证得出,可以利用CWARTS诊断工具可靠地评估皮肤疣的外观。

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/bjd.16299

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