Surface functionalization of superparamagnetic nanoparticles by an acid-liable polysaccharide-based prodrug for combinatorial monitoring and chemotherapy of hepatocellular carcinoma

5 years ago

Surface functionalization of superparamagnetic nanoparticles by an acid-liable polysaccharide-based prodrug for combinatorial monitoring and chemotherapy of hepatocellular carcinoma

Li-Ming Zhang, Meng Qi, Li Wang, Chaoping Fu, Xin-Qing Jiang, Nan-nan Li, Rui-Meng Yang, Xin-hua Wei, Xiang-dong Xu

For combinatorial monitoring and chemotherapy of liver carcinoma, the macromolecular prodrug based on hyaluronic acid and doxorubicin hydrochloride was prepared by an acid-labile linkage and conjugated with amine-modified iron oxide nanoparticles.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/QkCoQgHJW5M/C7RA05042A

DOI: 2017/RA/C7RA05042A

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