Polymer Chemistry
Polymer Chemistry
5 years ago

Structure-cytotoxicity relationship of drug-initiated polymer prodrug nanoparticles

Structure-cytotoxicity relationship of drug-initiated polymer prodrug nanoparticles
Julien Nicolas, Yinyin Bao
Cladribine (CdA)-based polymer prodrug nanoparticles were obtained by "drug-initiated" RAFT polymerization of squalenyl methacrylate (SqMA) from two different CdA-bearing chain transfer agents (CTAs) to evaluate the influence of the nature of the linkage between CdA and the CTA, and the bulkiness of the polymer, on the drug release and the biological performance.

Publisher URL: http://feeds.rsc.org/~r/rss/PY/~3/vSgY31J7rb8/C7PY00536A

DOI: 2017/PY/C7PY00536A

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