The Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides

5 years ago

The Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides

Daniel Oehlrich, Carolina Martínez-Lamenca, Joseph E. Leenaerts, Charlotte S. Richards-Taylor, Andres A. Trabanco

A general synthesis of CF₃-sulfonimidamides from sulfinamides under both batch and continuous flow conditions is described. The reaction proceeds via a sulfonimidoyl fluoride intermediate. A reaction scope showing good group variation on the substituents of both nitrogen atoms is also presented.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b01628

DOI: 10.1021/acs.joc.7b01628

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