Tetrahedron
Tetrahedron
5 years ago

Silver-catalyzed tandem nucleophilic addition/cycloisomerization of ortho-alkynylbenzaldehydes: Regioselective synthesis of functionalized 1H-isochromene derivatives

Silver-catalyzed tandem nucleophilic addition/cycloisomerization of ortho-alkynylbenzaldehydes: Regioselective synthesis of functionalized 1H-isochromene derivatives
An efficient silver-catalyzed domino cycloisomerization reaction for regioselective assembly of 1H-isochromene derivatives from o-alkynylaryl aldehydes with enaminones as the external nuclephiles is developed. This protocol affords isochromene derivatives in moderate to good yields under simple and mild reaction conditions.

Publisher URL: www.sciencedirect.com/science

DOI: S0040402017308025

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.