Human Reproduction Update
Human Reproduction Update
5 years ago

IUI: review and systematic assessment of the evidence that supports global recommendations.

Willem Ombelet, Sheryl Van der Poel, Ben Cohlen, Aartjan Bijkerk
IUI with or without ovarian stimulation (OS) has become a first-line treatment option for many infertile couples, worldwide. The appropriate treatment modality for couples and their clinical management through IUI or IUI/OS cycles must consider maternal and perinatal outcomes, most notably the clinical complication of higher-order multiple pregnancies associated with IUI-OS. With a current global emphasis to continue to decrease maternal and perinatal mortality and morbidity, the World Health Organization (WHO) had established a multi-year project to review the evidence for the establishment of normative guidance for the implementation of IUI as a treatment to address fertility problems, and to consider its cost-effectiveness for lower resource settings.

Publisher URL: http://doi.org/10.1093/humupd/dmx041

DOI: 10.1093/humupd/dmx041

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