5 years ago

Comparison of Generic Fluorescent Markers for Detection of Extracellular Vesicles by Flow Cytometry.

Frank A W Coumans, Zoltan Varga, Edwin van der Pol, Rienk Nieuwland, Leonie de Rond, Chi M Hau, Auguste Sturk, Ton G van Leeuwen
Extracellular vesicles (EVs) in biofluids are potential biomarkers of disease. To explore the clinical relevance of EVs, a specific generic EV marker would be useful, one that does not require antibodies and binds to all EVs. Here we evaluated 5 commonly used generic markers for flow cytometry.

Publisher URL: http://doi.org/10.1373/clinchem.2017.278978

DOI: 10.1373/clinchem.2017.278978

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