5 years ago

Synthetic Access to Oxazolidin-4-ones via Elimination/[3+2] Cycloaddition Reaction

Synthetic Access to Oxazolidin-4-ones via Elimination/[3+2] Cycloaddition Reaction
Guofu Zhong, Kai Li, Limin Yang, Jun Yan, Shengsheng Jiang, Chengtao Zhao, Kuangxi Shi
Elimination/[3+2] cycloaddition reactions of simple enals and unprotected isatins with haloamides have been developed. This transformation provides rapid access to highly functionalized oxazolidin-4-ones that are represented in bioactive compounds.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b00547

DOI: 10.1021/acs.joc.7b00547

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