3 years ago

Frontispiece: Twisted Amides: From Obscurity to Broadly Useful Transition-Metal-Catalyzed Reactions by N−C Amide Bond Activation

Frontispiece: Twisted Amides: From Obscurity to Broadly Useful Transition-Metal-Catalyzed Reactions by N−C Amide Bond Activation
Michal Szostak, Chengwei Liu
Twisted amides: The use of amide bond twist (distortion) has advanced to the general organic chemistry mainstream enabling a host of highly attractive N−C amide bond cross-coupling reactions of broad synthetic relevance. In their Minireview, M. Szostak and C. Liu on page 7157 ff. discuss recent progress in this area and provide a detailed overview of the prominent role of amide bond twist as a driving force in the development of transition-metal-catalyzed cross-coupling reactions by N−C amide bond activation.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201783061

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