Chemistry - A European Journal
Chemistry - A European Journal
5 years ago

Decarboxylation as the Key Step in C−C Bond-Forming Reactions

Decarboxylation as the Key Step in C−C Bond-Forming Reactions
Debabrata Maiti, Tuhin Patra
C−C bond forming reactions incarnate the core of organic synthesis because of their fundamental applications to molecular diversity and complexity. In recent years, use of carboxylic acid as one of the coupling partners in place of conventional organometallic reagents has seen an upsurge due to its potency to generate similar organometallic intermediates after decarboxylation. This Review provides an overview on the most recent progress in the field of C−C bond formation involving decarboxylation as a key step. Different important developments, which are not included in earlier Reviews in this area, have been summarized with representative examples and discussions on their reaction mechanisms. C here: This Review article covers the recent and important developments in the rapidly growing field of decarboxylative C−C bond formation.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201604496

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