Anesthesiology
Anesthesiology
5 years ago

Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome.

Joana A Machado, Thea Koch, Anna Carolinna Carvalho, Marcelo M Morales, Cynthia Dos S Samary, Lillian Moraes, Cíntia L Santos, Eliete F Pinto, Patricia R M Rocco, Vera L Capelozzi, Milena V Oliveira, Ligia de A Maia, Paolo Pelosi, Vanessa Martins, Raquel S Santos, Marcelo Gama de Abreu, Pedro L Silva, Marcos Vinícius de S Fernandes
The authors hypothesized that low tidal volume (VT) would minimize ventilator-induced lung injury regardless of the degree of mechanical power. The authors investigated the impact of power, obtained by different combinations of VT and respiratory rate (RR), on ventilator-induced lung injury in experimental mild acute respiratory distress syndrome (ARDS).

Publisher URL: http://doi.org/10.1097/ALN.0000000000002143

DOI: 10.1097/ALN.0000000000002143

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