Identification of inhibitors of the immunosuppressive enzyme IL4I1
Highlights
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Identification of easily synthesizable phenylalanine derivatives inhibitors of the immunosuppressive enzyme Interleukin 4-induced gene 1 (IL4I1).
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reversion of IL4I1 inhibitory effect on primary T lymphocytes proliferation by the compound 2-SO4.
Graphical abstract
Publisher URL: https://www.sciencedirect.com/science/article/pii/S0045206819309174
DOI: 10.1016/j.bioorg.2019.103463
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