5 years ago

The Accuracy of the ADOS-2 in Identifying Autism among Adults with Complex Psychiatric Conditions

Judith S. Miller, Katherine Mullan, Monica E. Calkins, Brenna B. Maddox, Kathleen Shea, David S. Mandell, Jack Hostager, Edward S. Brodkin

Abstract

The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Module 4 is considered a “gold-standard” instrument for diagnosing autism spectrum disorder (ASD) in adults. Although the ADOS-2 shows good sensitivity and specificity in lab-based settings, it is unknown whether these results hold in community clinics that serve a more psychiatrically impaired population. This study is the first to evaluate the diagnostic accuracy of the ADOS-2 among adults in community mental health centers (n = 75). The ADOS-2 accurately identified all adults with ASD; however, it also had a high rate of false positives among adults with psychosis (30%). Findings serve as a reminder that social communication difficulties measured by the ADOS-2 are not specific to ASD, particularly in clinically complex settings.

Publisher URL: https://link.springer.com/article/10.1007/s10803-017-3188-z

DOI: 10.1007/s10803-017-3188-z

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