Organic Letters
Organic Letters
5 years ago

Synthesis of Geminal Azido–Halo Compounds and α-Azidoalkyl Esters from Aldehydes via α-Azido Alcohols

Synthesis of Geminal Azido–Halo Compounds and α-Azidoalkyl Esters from Aldehydes via α-Azido Alcohols
Klaus Banert, Christian Berndt, Kevin Weigand
α-Azido alcohols are generated by treating aldehydes with hydrazoic acid in chloroform. These adducts are transformed into geminal azido–halo compounds through the reaction with phosphorus trichloride or phosphorus tribromide, whereas α-azidoalkyl esters are isolated after interaction with acyl chlorides.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b02380

DOI: 10.1021/acs.orglett.7b02380

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.