British Journal of Dermatology
British Journal of Dermatology
5 years ago

Olmutinib-induced palmoplantar keratoderma

Y. S. Sheen, Y. T. Cho, C. W. Liang, C. W. Yang, C.Y. Chu, K. L. Chen, M. E. Lacouture
olmutinib is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for the treatment of non-small cell lung cancer (NSCLC), especially for those harboring T790M mutations, the most common reason for other EGFR-TKI resistance. We describe three patients who developed acquired palmoplantar keratoderma (PPK) after taking olmutinib, an adverse event which has not been reported in previous generations of EGFR-TKIs. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/bjd.15935

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