5 years ago

Oral mucosa is a useful substrate for detecting autoantibodies of mucous membrane pemphigoid

T. Asaka, W. Nishie, K. Natsuga, H. Iwata, K. Izumi, M. Kamaguchi, H. Shimizu, Y. Kitagawa, H. Ujiie
Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease targeting various autoantigens, including the C-terminus of collagen XVII (COL17) and laminin332. Bullous pemphigoid (BP) is the most common autoimmune blistering disease, affecting the mucosae in 10-20% of cases. COL17, particularly, the non-collagenous (NC)16A domain is the pathogenic epitope for BP. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/bjd.15925

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