4 years ago

Safety and efficacy of topical timolol treatment of infantile haemangioma: A prospective trial

J. Proudfoot, S. Admani, P. Gangar, S. F. Friedlander, J. Borok
Topical timolol therapy is considered a relatively “safer” alternative for the treatment of infantile haemangiomas (IH); however, sufficient supportive pharmacokinetic data does not exist. Most efficacy studies have not evaluated systemic absorption.1-5 To our knowledge, this is the first prospective trial to assess the clinical response of proliferating IH to topical timolol maleate 0.5% gel-forming solution and to determine if systemic absorption occurred.Twenty-six subjects enrolled in this trial approved by the UCSD IRB. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/bjd.15865

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