5 years ago

The effect of botulinum neurotoxin A in patients with plaque psoriasis – an exploratory trial

T. Todberg, K. Nielsen, K. K. Bonefeld, C. Zachariae, L. Skov, A. Bregnhøj, L. Iversen, L. Hedelund
A few case stories have described patients with psoriasis who suffered from nerve injury which resulted in clearance of psoriasis (1, 2). Recently three reports have addressed a positive effect of botulinum neurotoxin A (BoNT-A) injections in patients with psoriasis (3-5). BoNT-A inhibits neuropeptide releasement and inflammatory cytokines(6), thus the hypothesis was that blocking neuromodulator could lower neurogenic inflammation resulting in improvement of psoriasis. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/jdv.14536

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