3 years ago

Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles

Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles
Àngela Ribes, Pedro Amorós, Ramón Martínez-Máñez, Félix Sancenón, Elena Aznar, M. Dolores Marcos, Andrea Bernardos
Mesoporous silica nanoparticles loaded with rhodamine B and capped with a bisphenol A aptamer were used for the selective and sensitive detection of this lethal chemical. The pores of the nanoparticles are selectively opened in the presence of bisphenol A (through its selective coordination with the aptamer) with subsequent rhodamine B delivery. With this capped material a limit of detection as low as 3.5 μm of bisphenol A was measured. A new hybrid aptamer-capped mesoporous silica material has been developed for the selective and sensitive detection of Bisphenol A in water.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201701024

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