Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics
5 years ago

Cushing's syndrome caused by use of synthetic ocular steroid

Cushing's syndrome caused by use of synthetic ocular steroid
F. Kökali, M. A. Duman, A. Üstyol, M. Elevli, N. Duru
What is known and objective Cases of Cushing's syndrome (CS) following ocular steroid use have been reported in recent years, albeit rarely. Case description We report a case of iatrogenic CS in a child induced by fluorometholone-containing eyedrops. Our patient was referred to our endocrinology clinic due to rapid weight gain. His history revealed that 1.5 months previously he had been started on fluorometholone eyedrops. What is new and conclusion To the best of our knowledge, no cases of CS have been reported following ocular fluorometholone use. Although eyedrops containing potent glucocorticoids may lead to CS, fluorometholone, a relatively less potent steroid, may also cause the syndrome, as in our case. Appearance of child at diagnosis with Cushing’s syndrome(a) and after ceasing(b) ocular steroid. moon-like face disappeared after ceasing ocular fluorometholone.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/jcpt.12573

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