3 years ago

Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein

Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein
Taijiao Jiang, Hongwei Li, Zhe Guan, Jianguo Ji, Zhongmin Liu, Qiran Zhai, Xin Sun, Peng Zhang, Can Xie, Jingeng Mai, Luhua Lai, Qihui Zhu, Xuesong Hu, Qining Wang, Yao Kuang, Hong-Wei Wang, Tiantian Cai, Bin Xia, Hao Ruan, Xuanxuan Li, Shu-Jin Luo, Zeyang Li, Yunfeng Dou, Haiguang Liu

Summary

Cephalopods, the group of animals including octopus, squid, and cuttlefish, have remarkable ability to instantly modulate body coloration and patterns so as to blend into surrounding environments [1, 2] or send warning signals to other animals [3]. Reflectin is expressed exclusively in cephalopods, filling the lamellae of intracellular Bragg reflectors that exhibit dynamic iridescence and structural color change [4]. Here, we trace the possible origin of the reflectin gene back to a transposon from the symbiotic bioluminescent bacterium Vibrio fischeri and report the hierarchical structural architecture of reflectin protein. Intrinsic self-assembly, and higher-order assembly tightly modulated by aromatic compounds, provide insights into the formation of multilayer reflectors in iridophores and spherical microparticles in leucophores and may form the basis of structural color change in cephalopods. Self-assembly and higher-order assembly in reflectin originated from a core repeating octapeptide (here named protopeptide), which may be from the same symbiotic bacteria. The origin of the reflectin gene and assembly features of reflectin protein are of considerable biological interest. The hierarchical structural architecture of reflectin and its domain and protopeptide not only provide insights for bioinspired photonic materials but also serve as unique "assembly tags" and feasible molecular platforms in biotechnology.

Publisher URL: http://www.cell.com/current-biology/fulltext/S0960-9822(17)30965-X

DOI: 10.1016/j.cub.2017.07.061

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.