Cardiovascular highlights from non-cardiology journals
Transcatheter aortic valve replacement (TAVR) is superior to medical therapy in inoperable patients with severe, symptomatic aortic stenosis (AS), and may be the preferred option in high-risk surgical patients. The comparative efficacy of TAVR and surgical aortic valve replacement (SAVR) in intermediate-risk AS patients has been less well studied. The PARTNER 2 randomised trial showed non-inferiority of balloon expandable TAVR compared to SAVR in intermediate-risk patients at 2 years. In the Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI) trial, a self-expandable TAVR prosthesis (Medtronic’s CoreValve (84%) and Evolut R (16%)) was randomised against SAVR in 1660 intermediate-risk patients. The primary endpoint was a composite of death from any cause and disabling stroke at 24 months. The mean age was 79.8±6.2 years with an average Society of Thoracic Surgeons (STS) estimated risk of death of 4.5±1.6%. At 24 months, the...
Publisher URL: http://heart.bmj.com/cgi/content/short/103/18/1470
DOI: 10.1136/heartjnl-2017-311882
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