Vedolizumab safety in pregnancy and newborn outcomes
We read with interest the study by Colombel et al
VDZ (MLN0002, MLN02, LDP-02, anti-α4β7) is a humanised monoclonal IgG1 antibody targeting α4β7 integrin. IgG1 is the predominant means of fetal immunity and maternal–fetal transport across the placenta, which increases linearly throughout pregnancy.
The first two patients display typical IBD demographics, while...
Publisher URL: http://gut.bmj.com/cgi/content/short/66/10/1866
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