3 years ago

Bicuspid aortic valves and intracranial aneurysms: more than an incidental coexistence?

We read with great interest the manuscript by Egbe and coauthors from Mayo Clinic published in Heart.1 The authors focused on a clinically relevant manifestation of intracranial aneurysms (IAs) in patients diagnosed with a bicuspid aortic valve disease (BAV). A large institutional BAV cohort was retrospectively analysed while identifying those patients with BAV who had brain imaging with MRA. A total of 52 patients (7.7%) with IA were identified which were associated with seven adverse events during the follow-up (two aneurysm ruptures, four coil embolisations and three aneurysm enlargements >1 mm). Based on these findings, the authors stated an increased IA prevalence in patients with BAV, especially in those presenting with a concomitant aortic coarctation (ie, 12.9%). Furthermore, a clinically relevant association was revealed between proximal BAV-associated aortopathy and IA occurrence which may indicate a common pathophysiologic pathway in the aneurysm formation. Although the natural history of BAV-associated IA’s seems...

Publisher URL: http://heart.bmj.com/cgi/content/short/103/19/1477

DOI: 10.1136/heartjnl-2017-311482

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.