Current Medicinal Chemistry
Current Medicinal Chemistry
5 years ago

Electrochemical Immunosensors for Disease Detection and Diagnosis.

Hosu O, Cristea C, Marrazza G, Selvolini G
The detection of biological molecules referred as biomarkers in biological fluids is fundamental in clinical analysis because it permits to discriminate between healthy and ill individuals and to evaluate the progress of a disease. The ability to identify a disease at an early stage and/or with high precision is a primary element of successful therapeutic treatment, resulting in an improved life quality for individuals and in less social impact or cost of the health system. The development of immunosensors for the detection and monitoring of biomarkers is currently a major area of research and, as more markers are discovered and their role in disease becomes better understood, this will continue to grow. The success of these biosensors is largely due to the properties of the antibodies used to capture and detect the analyte, because of the high sensitivity and specificity of immunoglobulins. Herein, we report the research progresses of electrochemical immunosensors applied in clinical analysis that have been published in the last years. Particularly, we focus our attention on the biomarker determination for diagnosis of malignant, cardiac and autoimmune diseases.

Publisher URL: https://www.ncbi.nlm.nih.gov/pubmed/28748767

DOI: PubMed:28748767

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.