3 years ago

Cerium doped magnetite nanoparticles for highly sensitive detection of metronidazole via chemiluminescence assay

Cerium doped magnetite nanoparticles for highly sensitive detection of metronidazole via chemiluminescence assay
Yasin Orooji, Mahsa Haddad Irani-nezhad, Ramin Hassandoost, Alireza Khataee, Shima Rahim Pouran, Sang Woo Joo

Cerium doped magnetite nanoparticle (CDM) was synthesized via a co-precipitation method and used as the co-reactant of luminol-K3Fe(CN)6 chemiluminescent system. The physical-chemical features of CDM were studied by XPS, XRD, HRTEM, FESEM, VSM, BET, and FTIR analyses. This simple and highly sensitive nanoprobe enabled the determination of minor concentrations of metronidazole (MNZ). Owing to the quenching efficacy of MNZ in the studied chemiluminescence system, a linear range of 3.47 × 10−6-9.37 × 10−5 mol/L was obtained with a limit of detection of 3.91 × 10−7 mol/L. This biosensor was used for MNZ detection in human serum samples, which was highly efficient. The outcomes of this study give credit to the proposed biosensor to be applied for detection of MNZ in biological samples.

Publisher URL: https://www.sciencedirect.com/science/article/pii/S138614252030250X

DOI: 10.1016/j.saa.2020.118272

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.