4 years ago

Response to Raschi E and colleagues "Reduced reporting of neuropsychiatric adverse events with tumor necrosis factor alpha inhibitors for hidradenitis suppurativa: caution before concluding for risk reduction"

M.A. Gupta, B. Vujcic, A.K. Gupta

We appreciate the comments of Raschi and colleagues.1 We agree that the term for interpreting the reporting odds ratio (ROR) in our study2 should be "lower than expected reporting of suicidal behaviours with anti‐TNFα drugs" and not "reduced risk". We recognize 1,2 that the ROR does not offer risk quantification; however, in the spirit of mining for safety signals in the FAERS database, terms that may be interpreted as referring to risk quantification, have been used.3 We thank Raschi and colleagues1 for highlighting our oversight.

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