4 years ago

Target product profiles for the diagnosis of <i>Taenia solium</i> taeniasis, neurocysticercosis and porcine cysticercosis

Piero L. Olliaro, Bernadette Abela-Ridder, Anna S. Fahrion, Meritxell Donadeu

by Meritxell Donadeu, Anna S. Fahrion, Piero L. Olliaro, Bernadette Abela-Ridder

Target Product Profiles (TPPs) are process tools providing product requirements to guide researchers, developers and manufacturers in their efforts to develop effective and useful products such as biologicals, drugs or diagnostics. During a WHO Stakeholders Meeting on Taenia solium diagnostics, several TPPs were initiated to address diagnostic needs for different stages in the parasite’s transmission (taeniasis, human and porcine cysticercosis). Following the meeting, draft TPPs were completed and distributed for consultation to 100 people/organizations, including experts in parasitology, human and pig cysticercosis, diagnostic researchers and manufacturers, international organizations working with neglected or zoonotic diseases, Ministries of Health and Ministries of Livestock in some of the endemic countries, WHO regional offices and other interested parties. There were 53 respondents. All comments and feedback received were considered and discussions were held with different experts according to their area of expertise. The comments were consolidated and final TPPs are presented here. They are considered to be live documents which are likely to undergo review and updating in the future when new knowledge and technologies become available.

Publisher URL: http://journals.plos.org/plosntds/article

DOI: 10.1371/journal.pntd.0005875

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