Tetrahedron
Tetrahedron
5 years ago

A facile method to enable a model phospholipid cell-permeable and photoactivatable

A facile method to enable a model phospholipid cell-permeable and photoactivatable
Directly utilizing phospholipids in cellular studies is limited by their dynamic metabolism and lack of cell permeability. We have developed a facile method to enable a fluorescent model phospholipid cell-permeable and photoactivatable. This method features the reaction of a diazo-containing molecule with either phosphonic or phosphoric acids to form the corresponding photocaged esters under mild conditions, and should be generally applicable to endogenous phospholipids.

Publisher URL: www.sciencedirect.com/science

DOI: S0040402017303988

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