STR-324, a Stable Analog of Opiorphin, Causes Analgesia in Postoperative Pain by Activating Endogenous Opioid Receptor-dependent Pathways

5 years ago

STR-324, a Stable Analog of Opiorphin, Causes Analgesia in Postoperative Pain by Activating Endogenous Opioid Receptor-dependent Pathways

Benhamou, D., Hamdi, L., Sitbon, P., Mazoit, J. X., Rougeot, C., Van Elstraete, A., Juarez-Perez, V.

(Abstracted from Anesthesiology, 125(5):1017–1029, 2016) Opiorphin is a natural human peptide with strong analgesic properties. These analgesic effects thought to result in a reduction in enkephalin hydrolysis secondary to the compound inhibition of enkephalinase.

Publisher URL: http://journals.lww.com/surveyanesthesiology/Fulltext/2017/06000/STR_324,_a_Stable_Analog_of_Opiorphin,_Causes.35.aspx

DOI: 10.1097/01.sa.0000521825.85774.2d

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