5 years ago

The Analgesic Efficacy of Nonsteroidal Anti-Inflammatory Agents (NSAIDs) in Patients Undergoing Cesarean Deliveries: A Meta-Analysis

Murphy, J.D., Nami, N.F., Wu, C.L., Zeng, A.M.
(Reg Anesth Pain Med. 2016;41(6):763–772) In 2007, there were 1.4 million cesarean deliveries (1 in 3 live births) in the United States alone. Pain after cesarean delivery can be severe in many patients, with 78% of women undergoing cesarean delivery reporting moderate to severe postoperative pain within the first 24 hours postoperatively. Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of this postoperative pain despite them being generally viewed as “weak” analgesics. This meta-analysis was conducted to assess the analgesic efficacy of NSAIDs in postoperative cesarean delivery patients as well as secondary outcomes such as opioid-related adverse side effects and quality of breastfeeding.
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