3 years ago

A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light

A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light
Alberto Gasco, Salvatore Sortino, Barbara Rolando, Roberta Fruttero, Loretta Lazzarato, Aurore Fraix, Marco Blangetti, Federica Sodano, Elisabetta Marini
Using a facile synthetic route, an organic NO release agent based on a BODIPY light-harvesting antenna was devised. This compound is stable in the dark and delivers NO under photoexcitation with biologically favorable green light. Temporally regulated vasodilation capability is demonstrated on rat aorta by green-light-induced NO release. NO? Yes! Using a facile synthetic route, an organic NO release agent based on a BODIPY light-harvesting antenna was devised. This compound is stable in the dark and delivers NO under photoexcitation with green light.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201701889

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