4 years ago

Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

Hadzic, Nedim, Baumann, Ulrich, Ozgenç, Funda, Socha, Piotr, Colledan, Michele, Toso, Christian, d’Antiga, Lorenzo, Karam, Vincent, Dhawan, Anil, Verma, Anita, Falk, Christine, McLin, Valérie A., Franchi-Abella, Stéphanie, Goyet, Jean de Ville de, Boyer, Olivia, Nobili, Valerio, Feng, Sandy, Sciveres, Marco, Debray, Dominique, Horslen, Simon, Bucuvalas, John, Maecker-Kolhoff, Britta, Vajro, Pietro, Reding, Raymond, Durmaz, Ozlem, Cuturi, Maria-Cristina, Mazariegos, George, Hierro, Loreto, Wildhaber, Barbara E., Kelly, Deirdre, Dezsofi, Antal, Sharif, Khalid, Hubscher, Stefan, Ganschow, Rainer, Frauca, Esteban, Allen, Upton, Gottschalk, Stephen, Fischler, Björn, McKiernan, Patrick, Melk, Anette
imageABSTRACT: As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.
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