Organic Letters
Organic Letters
5 years ago

Galactomannan from Antrodia cinnamomea Enhances the Phagocytic Activity of Macrophages

Galactomannan from Antrodia cinnamomea Enhances the Phagocytic Activity of Macrophages
Jung-Feng Hsieh, Yueh-Tung Lu, Yi-Ting Tsai, Kuo-Feng Hua, Shih-Hsiung Wu, Lan-Hui Li, Ching-Ming Chang, Feng-Ling Yang, Shih-Hao Zhan, Namal Perera
Galactomannan with an octasaccharide-repeating unit (ACP) was isolated from Taiwan medicinal mushroom Antrodia cinnamomea, and its chemical structure was determined herein. ACP significantly enhanced the phagocytosis and bactericidal activity of J774A.1 murine macrophages against Escherichia coli, with prospects for developing a new immunomodulatory compound or adjuvant in immunotherapy and vaccination.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b01468

DOI: 10.1021/acs.orglett.7b01468

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.