4 years ago

Antineutrophil cytoplasmic antibodies: reporting and diagnostic strategies

It was with great interest that we read the correspondence of Mahler and Fritzler1 on our recent European Vasculitis Study Group (EUVAS) study describing the performance of immunoassays for antineutrophil cytoplasmic antibodies (ANCA) in patients with ANCA-associated vasculitides (AAV).2 In their letter, Mahler and Fritzler raise some interesting points, mainly related to (i) test result interpretation and (ii) diagnostic strategies. Besides, they pointed out that in the EUVAS study only two indirect immunofluorescence (IIF) assays were included, a commercial assay from Inova Diagnostics and a ‘home-made’ assay. They suggested to perform studies with more than two IIF ANCA tests and especially to include assays that are most commonly used in diagnostic laboratories. In a concomitant publication, we presented data on two additional commercial IIF assays, one from Euroimmun and one from Medipan.3 Accordingly, we postulate that we included the most commonly used IIF...

Publisher URL: http://ard.bmj.com/cgi/content/short/76/10/e39

DOI: 10.1136/annrheumdis-2017-211171

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.