Tetrahedron
Tetrahedron
5 years ago

A three-component one-pot synthesis of penta-substituted pyrroles via ring opening of α-nitroepoxides

A three-component one-pot synthesis of penta-substituted pyrroles via ring opening of α-nitroepoxides
A novel and facile one-pot reaction has been developed to synthesize a variety of penta-substituted pyrroles from α-nitroepoxides, primary amines and dialkyl acetylenedicarboxylates under the conditions without catalyst. Furthermore, the controlled experiments has been performed and a possible mechanism has also been proposed.

Publisher URL: www.sciencedirect.com/science

DOI: S0040402017303319

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